Meaning, Origin & Family History (2024)

Table of Contents
The meaning of Niemi How common is the last name Niemi in the United States? Race and Ethnicity of people with the last name Niemi Niemi ancestry composition Possible origins of the surname Niemi What Niemi haplogroups can tell you Your paternal lineage may be linked to many northern European men Your maternal lineage may be linked to Marie Antoinette What do people with the surname Niemi have in common? Preferences Chocolate Ice Cream Vanilla Ice Cream Like Very Cold Weather Likes Sweets Stawberry Ice Cream Likes Hoppy Beer Likes Boiled Eggs Chocolate Ice Cream Vanilla Ice Cream Like Very Cold Weather Likes Sweets Stawberry Ice Cream Likes Hoppy Beer Likes Boiled Eggs Chocolate Ice Cream Vanilla Ice Cream Like Very Cold Weather Likes Sweets Stawberry Ice Cream Likes Hoppy Beer Likes Boiled Eggs Traits Misophonia Cheek Dimples Acrophobia Light Hair Straight Hair Misophonia Cheek Dimples Acrophobia Light Hair Straight Hair Misophonia Cheek Dimples Acrophobia Light Hair Straight Hair Habits Sugary Drink Vitamin Use Kinesthetic Learner Tea Consumption Learn Language As Adult Verbal Learner Sugary Drink Vitamin Use Kinesthetic Learner Tea Consumption Learn Language As Adult Verbal Learner Sugary Drink Vitamin Use Kinesthetic Learner Tea Consumption Learn Language As Adult Verbal Learner Wellness Migraine Cat Allergy Dog Allergy Migraine Cat Allergy Dog Allergy Migraine Cat Allergy Dog Allergy Are health conditions linked to the last name Niemi? Age-Related Macular Degeneration Hereditary Hemochromatosis (HFE-Related) Late-Onset Alzheimer's Disease Celiac Disease Celiac Disease Hereditary Hemochromatosis (HFE-Related) Alpha-1 Antitrypsin Deficiency Hereditary Thrombophilia Alpha-1 Antitrypsin Deficiency Cystic Fibrosis Age-Related Macular Degeneration Hereditary Hemochromatosis (HFE-Related) Late-Onset Alzheimer's Disease Celiac Disease Celiac Disease Hereditary Hemochromatosis (HFE-Related) Alpha-1 Antitrypsin Deficiency Hereditary Thrombophilia Alpha-1 Antitrypsin Deficiency Cystic Fibrosis Age-Related Macular Degeneration Hereditary Hemochromatosis (HFE-Related) Late-Onset Alzheimer's Disease Celiac Disease Celiac Disease Hereditary Hemochromatosis (HFE-Related) Alpha-1 Antitrypsin Deficiency Hereditary Thrombophilia Alpha-1 Antitrypsin Deficiency Cystic Fibrosis

The meaning of Niemi

Finnish: ornamental name from niemi ‘headland, spit’, adopted largely in the late 19th century by Finns without surnames and during the early 20th century name-changing campaigns to replace Swedish surnames (compare Laine 4). In part, however, this is a habitational name from farms so named, with reference to their location. In North America, Niemi is also found a shortened form of other surnames containing this element, such as Rajaniemi and Sotaniemi. Some characteristic forenames: Finnish Eino, Reino, Arvo, Waino, Eero, Niilo, Urho, Armi, Lempi, Onni, Sulo, Vieno.

Dictionary of American Family Names, 2nd edition, © Oxford University Press, 2022.

How common is the last name Niemi in the United States?

Based on the Decennial U.S. Census data, the surname Niemi experienced a slight decrease in popularity between 2000 and 2010. In 2000, Niemi was ranked as the 7234th most popular surname, but by 2010 it had slipped to the 7767th position, representing a change of -7.37%. However, despite this drop in rank, the actual count of individuals with the Niemi surname slightly increased from 4253 to 4272 during the same time period. The proportion per 100,000 people also saw a small decrease of -8.23%, moving from 1.58 in 2000 to 1.45 in 2010.

20002010Change
Rank#7,234#7,767-7.37%
Count4,2534,2720.45%
Proportion per 100k1.581.45-8.23%

Race and Ethnicity of people with the last name Niemi

The ethnic identity associated with the Niemi surname shifted somewhat over the 10-year span from 2000 to 2010, according to Decennial U.S. Census data. In 2000, the majority of those with the Niemi surname identified as White (96.38%), but this percentage decreased slightly to 94.73% by 2010. There was also a notable increase in individuals identifying as two or more races, going from 0.96% to 1.83%. Although still a small portion, the number of Niemis identifying as Asian/Pacific Islander also increased from 0.40% to 0.51%, and there was a rise in those identifying as Hispanic, from 1.18% to 1.83%. The percentages for Black and American Indian and Alaskan Native ethnicity remained relatively stable.

20002010Change
White96.38%94.73%-1.71%
Two or More Races0.96%1.83%90.63%
Hispanic1.18%1.83%55.08%
American Indian and Alaskan Native0.82%0.84%2.44%
Asian/Pacific Islander0.4%0.51%27.5%
Black0.26%0.26%0%

Niemi ancestry composition

23andMe computes an ancestry breakdown for each customer. People may have ancestry from just one population or they may have ancestry from several populations. The most commonly-observed ancestry found in people with the surname Niemi is British & Irish, which comprises 28.3% of all ancestry found in people with the surname. The next two most common ancestries are Finnish (26.5%) and French & German (20.0%). Additional ancestries include Scandinavian, Eastern European, Italian, Greek & Balkan, and Korean.

Ready to learn more about your ancestry? Get the most comprehensive ancestry breakdown on the market by taking our DNA test. Shop 23andMe

ANCESTRY BREAKDOWNCOMPOSITION
British & Irish28.3%
Finnish26.5%
French & German20.0%
Other25.1%

Meaning, Origin & Family History (1)

Possible origins of the surname Niemi

Your DNA provides clues about where your recent ancestors may have lived. Having many distant relatives in the same location suggests that you may all share common ancestry there. Locations with many distant relatives can also be places where people have migrated recently, such as large cities. If a large number of individuals who share your surname have distant relatives in a specific area, it could indicate a connection between your surname and that location, stemming from either recent ancestral ties or migration.

Based on 23andMe data, people with last name Niemi have recent ancestry locations spanning a few countries, mostly in the United Kingdom of Great Britain and Northern Ireland, and Ireland.

RECENT ANCESTRY LocationPercentage
West Midlands, United Kingdom68.50%
Merseyside, United Kingdom68.50%
Glasgow City, United Kingdom68.50%
Greater London, United Kingdom68.50%
West Yorkshire, United Kingdom67.70%

What Niemi haplogroups can tell you

Haplogroups are genetic population groups that share a common ancestor on either your paternal or maternal line. These paternal and maternal haplogroups shed light on your genetic ancestry and help tell the story of your family.

The top paternal haplogroup of people with the surname Niemi is I-L258, which is predominantly found among people with European ancestry. Haplogroup I-L258 is descended from haplogroup I-M170. Other common haplogroups include N-CTS1737 and N-M178, which are predominantly found among people with European and European ancestry. Other surnames with similar common haplogroups are: Maki, Kangas, Aho, Koski, Mattson, Erickson, Hendrickson, Peterson, Danielson, Gustafson.

The most common maternal haplogroups of people with Niemi surname are: H1, H, T2. These most commonly trace back to individuals of European ancestry.

Meaning, Origin & Family History (2)Paternal Haplogroup Origins I-M170

Meaning, Origin & Family History (3)

Your paternal lineage may be linked to many northern European men

If you have haplogroup I1a1b, your paternal line stems from a young branch of I-M253 called I-L22, which likely arose in the last 3,000 years. I-L22 is most common in Northern Europe, but a recent study found that this haplogroup was present in a significant portion of the Partecipanza population living in San Giovanni in Persiceto, Italy. The area of San Giovanni in Persiceto was involved in a migration period in 728 AD, when it became part of the Lombard kingdom, under King Aistulf. San Giovanni in Persiceto was only under Lombard rule for 48 years, after which the Lombards were defeated by King Charlemagne in 776 AD. There are several characteristics of San Giovanni in Persiceto that link it to other Lombard settlements. For instance, some research suggests San Giovanni in Persiceto was the seat of a Lombard Duke between 750 and 800 AD. It is possible that the Lombards who ruled over San Giovanni in Persiceto played an important role in the introduction and growth of haplogroup I-L22 in the region.

Your maternal lineage may be linked to Marie Antoinette

Because it is so dominant in the general European population, haplogroup H also appears quite frequently in the continent's royal houses. Marie Antoinette, an Austrian Hapsburg who married into the French royal family, inherited the haplogroup from her maternal ancestors. So did Prince Philip, Duke of Edinburgh, whose recorded genealogy traces his female line to Bavaria. Scientists also discovered that famed 16th century astronomer Nicolaus Copernicus traced his maternal lineages to haplogroup H.

Meaning, Origin & Family History (4)

What do people with the surname Niemi have in common?

Spoiler alert: it's complicated. People with the same last name are usually no more genetically similar than a randomly sampled group of people from the same population. That said, people with the same surname are more likely to have similar ancestries than randomly sampled individuals. The reason is the tendency of people with similar cultural or geographical backgrounds to preferentially mate with one another. That's why people who share a surname may be more likely to share traits and tendencies in common than people within the general population. Check out the percentages below to see the prevalences of tastes, habits, and traits of people with your surname compared with prevalences among 23andMe users.

Preferences

Meaning, Origin & Family History (5)

Chocolate Ice Cream

Prefers chocolate flavored ice cream over other flavors.

"Niemi" Surname 38.9%

23andMe Users 41.3%

Meaning, Origin & Family History (6)

Vanilla Ice Cream

Prefers vanilla flavored ice cream over other flavors.

"Niemi" Surname 37.0%

23andMe Users 36.7%

Meaning, Origin & Family History (7)

Like Very Cold Weather

Enjoys weather that is colder than 40 degrees Farenheit

"Niemi" Surname 20.5%

23andMe Users 24.8%

Meaning, Origin & Family History (8)

Likes Sweets

Enjoys eating sweets more than other people.

"Niemi" Surname 29.6%

23andMe Users 33.8%

Meaning, Origin & Family History (9)

Stawberry Ice Cream

Prefers strawberry flavored ice cream over other flavors.

"Niemi" Surname 14.8%

23andMe Users 14.7%

Meaning, Origin & Family History (10)

Likes Hoppy Beer

Like beer that has a strong hop flavor and aroma.

"Niemi" Surname 26.3%

23andMe Users 20.0%

Meaning, Origin & Family History (11)

Likes Boiled Eggs

Likes the taste of hard-boiled eggs.

"Niemi" Surname 66.7%

23andMe Users 70.2%

Meaning, Origin & Family History (12)

Chocolate Ice Cream

Prefers chocolate flavored ice cream over other flavors.

"Niemi" Surname 38.9%

23andMe Users 41.3%

Meaning, Origin & Family History (13)

Vanilla Ice Cream

Prefers vanilla flavored ice cream over other flavors.

"Niemi" Surname 37.0%

23andMe Users 36.7%

Meaning, Origin & Family History (14)

Like Very Cold Weather

Enjoys weather that is colder than 40 degrees Farenheit

"Niemi" Surname 20.5%

23andMe Users 24.8%

Meaning, Origin & Family History (15)

Likes Sweets

Enjoys eating sweets more than other people.

"Niemi" Surname 29.6%

23andMe Users 33.8%

Meaning, Origin & Family History (16)

Stawberry Ice Cream

Prefers strawberry flavored ice cream over other flavors.

"Niemi" Surname 14.8%

23andMe Users 14.7%

Meaning, Origin & Family History (17)

Likes Hoppy Beer

Like beer that has a strong hop flavor and aroma.

"Niemi" Surname 26.3%

23andMe Users 20.0%

Meaning, Origin & Family History (18)

Likes Boiled Eggs

Likes the taste of hard-boiled eggs.

"Niemi" Surname 66.7%

23andMe Users 70.2%

Meaning, Origin & Family History (19)

Chocolate Ice Cream

Prefers chocolate flavored ice cream over other flavors.

"Niemi" Surname 38.9%

23andMe Users 41.3%

Meaning, Origin & Family History (20)

Vanilla Ice Cream

Prefers vanilla flavored ice cream over other flavors.

"Niemi" Surname 37.0%

23andMe Users 36.7%

Meaning, Origin & Family History (21)

Like Very Cold Weather

Enjoys weather that is colder than 40 degrees Farenheit

"Niemi" Surname 20.5%

23andMe Users 24.8%

Meaning, Origin & Family History (22)

Likes Sweets

Enjoys eating sweets more than other people.

"Niemi" Surname 29.6%

23andMe Users 33.8%

Meaning, Origin & Family History (23)

Stawberry Ice Cream

Prefers strawberry flavored ice cream over other flavors.

"Niemi" Surname 14.8%

23andMe Users 14.7%

Meaning, Origin & Family History (24)

Likes Hoppy Beer

Like beer that has a strong hop flavor and aroma.

"Niemi" Surname 26.3%

23andMe Users 20.0%

Meaning, Origin & Family History (25)

Likes Boiled Eggs

Likes the taste of hard-boiled eggs.

"Niemi" Surname 66.7%

23andMe Users 70.2%

Traits

Meaning, Origin & Family History (26)

Misophonia

When sounds made by others, like the sound of chewing or yawning, provoke strong emotional reactions in an individual.

"Niemi" Surname 29.5%

23andMe Users 27.9%

Meaning, Origin & Family History (27)

Cheek Dimples

Small indentations that appear on the cheeks when a person smiles.

"Niemi" Surname 27.6%

23andMe Users 37.6%

Meaning, Origin & Family History (28)

Acrophobia

An intense fear of heights that goes beyond the concern many people feel around significant heights.

"Niemi" Surname 34.1%

23andMe Users 16.7%

Meaning, Origin & Family History (29)

Light Hair

Hair that is blonde or light brown in color

"Niemi" Surname 64.3%

23andMe Users 50.5%

Meaning, Origin & Family History (30)

Straight Hair

Hair with strands that have no visible curl or wave.

"Niemi" Surname 37.0%

23andMe Users 30.5%

Meaning, Origin & Family History (31)

Misophonia

When sounds made by others, like the sound of chewing or yawning, provoke strong emotional reactions in an individual.

"Niemi" Surname 29.5%

23andMe Users 27.9%

Meaning, Origin & Family History (32)

Cheek Dimples

Small indentations that appear on the cheeks when a person smiles.

"Niemi" Surname 27.6%

23andMe Users 37.6%

Meaning, Origin & Family History (33)

Acrophobia

An intense fear of heights that goes beyond the concern many people feel around significant heights.

"Niemi" Surname 34.1%

23andMe Users 16.7%

Meaning, Origin & Family History (34)

Light Hair

Hair that is blonde or light brown in color

"Niemi" Surname 64.3%

23andMe Users 50.5%

Meaning, Origin & Family History (35)

Straight Hair

Hair with strands that have no visible curl or wave.

"Niemi" Surname 37.0%

23andMe Users 30.5%

Meaning, Origin & Family History (36)

Misophonia

When sounds made by others, like the sound of chewing or yawning, provoke strong emotional reactions in an individual.

"Niemi" Surname 29.5%

23andMe Users 27.9%

Meaning, Origin & Family History (37)

Cheek Dimples

Small indentations that appear on the cheeks when a person smiles.

"Niemi" Surname 27.6%

23andMe Users 37.6%

Meaning, Origin & Family History (38)

Acrophobia

An intense fear of heights that goes beyond the concern many people feel around significant heights.

"Niemi" Surname 34.1%

23andMe Users 16.7%

Meaning, Origin & Family History (39)

Light Hair

Hair that is blonde or light brown in color

"Niemi" Surname 64.3%

23andMe Users 50.5%

Meaning, Origin & Family History (40)

Straight Hair

Hair with strands that have no visible curl or wave.

"Niemi" Surname 37.0%

23andMe Users 30.5%

Habits

Meaning, Origin & Family History (41)

Sugary Drink

Drinks one or more sugary drinks per day.

"Niemi" Surname 20.3%

23andMe Users 21.1%

Meaning, Origin & Family History (42)

Vitamin Use

Takes vitamins on a regular basis.

"Niemi" Surname 53.1%

23andMe Users 45.5%

Meaning, Origin & Family History (43)

Kinesthetic Learner

Preferring to learn and process information through hands-on activities, practical experiences, and active engagement.

"Niemi" Surname 58.8%

23andMe Users 61.5%

Meaning, Origin & Family History (44)

Tea Consumption

A preference for drinking caffeinated tea in a particular week.

"Niemi" Surname 40.6%

23andMe Users 49.2%

Meaning, Origin & Family History (45)

Learn Language As Adult

Learning a new language through formal or informal means after 18 years of age.

"Niemi" Surname 20.6%

23andMe Users 25.8%

Meaning, Origin & Family History (46)

Verbal Learner

Preferring to learn and process information through words, both written and spoken.

"Niemi" Surname 29.4%

23andMe Users 22.9%

Meaning, Origin & Family History (47)

Sugary Drink

Drinks one or more sugary drinks per day.

"Niemi" Surname 20.3%

23andMe Users 21.1%

Meaning, Origin & Family History (48)

Vitamin Use

Takes vitamins on a regular basis.

"Niemi" Surname 53.1%

23andMe Users 45.5%

Meaning, Origin & Family History (49)

Kinesthetic Learner

Preferring to learn and process information through hands-on activities, practical experiences, and active engagement.

"Niemi" Surname 58.8%

23andMe Users 61.5%

Meaning, Origin & Family History (50)

Tea Consumption

A preference for drinking caffeinated tea in a particular week.

"Niemi" Surname 40.6%

23andMe Users 49.2%

Meaning, Origin & Family History (51)

Learn Language As Adult

Learning a new language through formal or informal means after 18 years of age.

"Niemi" Surname 20.6%

23andMe Users 25.8%

Meaning, Origin & Family History (52)

Verbal Learner

Preferring to learn and process information through words, both written and spoken.

"Niemi" Surname 29.4%

23andMe Users 22.9%

Meaning, Origin & Family History (53)

Sugary Drink

Drinks one or more sugary drinks per day.

"Niemi" Surname 20.3%

23andMe Users 21.1%

Meaning, Origin & Family History (54)

Vitamin Use

Takes vitamins on a regular basis.

"Niemi" Surname 53.1%

23andMe Users 45.5%

Meaning, Origin & Family History (55)

Kinesthetic Learner

Preferring to learn and process information through hands-on activities, practical experiences, and active engagement.

"Niemi" Surname 58.8%

23andMe Users 61.5%

Meaning, Origin & Family History (56)

Tea Consumption

A preference for drinking caffeinated tea in a particular week.

"Niemi" Surname 40.6%

23andMe Users 49.2%

Meaning, Origin & Family History (57)

Learn Language As Adult

Learning a new language through formal or informal means after 18 years of age.

"Niemi" Surname 20.6%

23andMe Users 25.8%

Meaning, Origin & Family History (58)

Verbal Learner

Preferring to learn and process information through words, both written and spoken.

"Niemi" Surname 29.4%

23andMe Users 22.9%

Wellness

Meaning, Origin & Family History (59)

Migraine

A severe headache characterized by intense pain, sensitivity to light and sound, and often accompanied by nausea and vomiting.

"Niemi" Surname 24.0%

23andMe Users 16.4%

Meaning, Origin & Family History (60)

Cat Allergy

An allergic reaction to cats, characterized by symptoms such as sneezing, itching, and difficulty breathing.

"Niemi" Surname 29.6%

23andMe Users 36.7%

Meaning, Origin & Family History (61)

Dog Allergy

An allergic reaction to dogs, characterized by symptoms such as sneezing, itching, and difficulty breathing.

"Niemi" Surname 20.8%

23andMe Users 23.3%

Meaning, Origin & Family History (62)

Migraine

A severe headache characterized by intense pain, sensitivity to light and sound, and often accompanied by nausea and vomiting.

"Niemi" Surname 24.0%

23andMe Users 16.4%

Meaning, Origin & Family History (63)

Cat Allergy

An allergic reaction to cats, characterized by symptoms such as sneezing, itching, and difficulty breathing.

"Niemi" Surname 29.6%

23andMe Users 36.7%

Meaning, Origin & Family History (64)

Dog Allergy

An allergic reaction to dogs, characterized by symptoms such as sneezing, itching, and difficulty breathing.

"Niemi" Surname 20.8%

23andMe Users 23.3%

Meaning, Origin & Family History (65)

Migraine

A severe headache characterized by intense pain, sensitivity to light and sound, and often accompanied by nausea and vomiting.

"Niemi" Surname 24.0%

23andMe Users 16.4%

Meaning, Origin & Family History (66)

Cat Allergy

An allergic reaction to cats, characterized by symptoms such as sneezing, itching, and difficulty breathing.

"Niemi" Surname 29.6%

23andMe Users 36.7%

Meaning, Origin & Family History (67)

Dog Allergy

An allergic reaction to dogs, characterized by symptoms such as sneezing, itching, and difficulty breathing.

"Niemi" Surname 20.8%

23andMe Users 23.3%

Are health conditions linked to the last name Niemi?

The short answer is that, if there is an association between surname and health, it's usually more about your ancestry than your name. Individuals with a given surname are no more genetically similar than the general population but often have similar ancestries. The populations of people associated with those shared ancestries often have sets of genetic variations, also known as alleles, in common. Some of those alleles are associated with a greater likelihood of developing certain diseases.

Disease variant frequency by ancestry

Disease allele frequencies in populations associated with the surname Niemi are shown below. Important Note: not everyone with a disease allele will develop these health condition

Age-Related Macular Degeneration

Y402H variant

Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss among older adults. The disease results in damage to the central part of the retina (the macula), impairing vision needed for reading, driving, or even recognizing faces. The 23andMe Health + Ancestry DNA test includes the two most common variants associated with an increased risk of developing the condition: the Y402H variant in the CFH gene and the A69S variant in the ARMS2 gene. Learn more about Age-Related Macular Degeneration

British & Irish 62.1%

23andMe Users 57.2%

Hereditary Hemochromatosis (HFE-Related)

H63D variant

Hereditary hemochromatosis is a genetic condition characterized by absorption of too much dietary iron. This may lead to iron overload, which can cause damage to the joints and certain organs, such as the liver, skin, heart, and pancreas. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this condition. Learn more about Hereditary Hemochromatosis (HFE-Related)

British & Irish 28.3%

23andMe Users 25.0%

Late-Onset Alzheimer's Disease

ε4 variant

Alzheimer's disease is characterized by memory loss, cognitive decline, and personality changes. Late-onset Alzheimer's disease is the most common form of Alzheimer's disease, developing after age 65. Many factors, including genetics, can influence a person's chances of developing the condition. The 23andMe Health + Ancestry DNA test includes the most common genetic variant associated with late-onset Alzheimer's disease: the ε4 variant in the APOE gene. Learn more about Late-Onset Alzheimer's Disease

British & Irish 28.2%

23andMe Users 25.5%

Celiac Disease

HLA-DQ2.5 variant

Celiac disease is an autoimmune condition in which the consumption of gluten (found in wheat, barley, and rye) can result in damage to the small intestine. Celiac disease can lead to both digestive and non-digestive problems. The 23andMe Health + Ancestry DNA test includes two common variants associated with an increased risk of developing this condition. Learn more about Celiac Disease

British & Irish 27.7%

23andMe Users 21.4%

Celiac Disease

HLA-DQ8 variant

Celiac disease is an autoimmune condition in which the consumption of gluten (found in wheat, barley, and rye) can result in damage to the small intestine. Celiac disease can lead to both digestive and non-digestive problems. The 23andMe Health + Ancestry DNA test includes two common variants associated with an increased risk of developing this condition. Learn more about Celiac Disease

British & Irish 18.9%

23andMe Users 20.0%

Hereditary Hemochromatosis (HFE-Related)

C282Y variant

Hereditary hemochromatosis is a genetic condition characterized by absorption of too much dietary iron. This may lead to iron overload, which can cause damage to the joints and certain organs, such as the liver, skin, heart, and pancreas. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this condition. Learn more about Hereditary Hemochromatosis (HFE-Related)

British & Irish 17.6%

23andMe Users 9.8%

Alpha-1 Antitrypsin Deficiency

PI*S variant

AAT deficiency is a genetic condition that can lead to lung and liver disease. It is caused by decreased levels of the alpha-1 antitrypsin (AAT) protein. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this deficiency: the PI*S and PI*Z variants in the SERPINA1 gene. Learn more about Alpha-1 Antitrypsin Deficiency

British & Irish 9.5%

23andMe Users 7.3%

Hereditary Thrombophilia

Factor V Leiden variant

Hereditary thrombophilia is a predisposition to developing harmful blood clots. These harmful blood clots most commonly form in the legs and can travel to the lungs. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to hereditary thrombophilia. Learn more about Hereditary Thrombophilia

British & Irish 4.2%

23andMe Users 4.5%

Alpha-1 Antitrypsin Deficiency

PI*Z variant

AAT deficiency is a genetic condition that can lead to lung and liver disease. It is caused by decreased levels of the alpha-1 antitrypsin (AAT) protein. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this deficiency: the PI*S and PI*Z variants in the SERPINA1 gene. Learn more about Alpha-1 Antitrypsin Deficiency

British & Irish 4.0%

23andMe Users 2.9%

Cystic Fibrosis

DeltaF508 variant

Cystic fibrosis is a rare genetic disorder characterized by impaired lung and digestive function. A person must have two variants in the CFTR gene in order to have this condition. Learn more about Cystic Fibrosis

British & Irish 3.5%

23andMe Users 2.3%

Age-Related Macular Degeneration

Y402H variant

Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss among older adults. The disease results in damage to the central part of the retina (the macula), impairing vision needed for reading, driving, or even recognizing faces. The 23andMe Health + Ancestry DNA test includes the two most common variants associated with an increased risk of developing the condition: the Y402H variant in the CFH gene and the A69S variant in the ARMS2 gene. Learn more about Age-Related Macular Degeneration

British & Irish 62.1%

23andMe Users 57.2%

Hereditary Hemochromatosis (HFE-Related)

H63D variant

Hereditary hemochromatosis is a genetic condition characterized by absorption of too much dietary iron. This may lead to iron overload, which can cause damage to the joints and certain organs, such as the liver, skin, heart, and pancreas. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this condition. Learn more about Hereditary Hemochromatosis (HFE-Related)

British & Irish 28.3%

23andMe Users 25.0%

Late-Onset Alzheimer's Disease

ε4 variant

Alzheimer's disease is characterized by memory loss, cognitive decline, and personality changes. Late-onset Alzheimer's disease is the most common form of Alzheimer's disease, developing after age 65. Many factors, including genetics, can influence a person's chances of developing the condition. The 23andMe Health + Ancestry DNA test includes the most common genetic variant associated with late-onset Alzheimer's disease: the ε4 variant in the APOE gene. Learn more about Late-Onset Alzheimer's Disease

British & Irish 28.2%

23andMe Users 25.5%

Celiac Disease

HLA-DQ2.5 variant

Celiac disease is an autoimmune condition in which the consumption of gluten (found in wheat, barley, and rye) can result in damage to the small intestine. Celiac disease can lead to both digestive and non-digestive problems. The 23andMe Health + Ancestry DNA test includes two common variants associated with an increased risk of developing this condition. Learn more about Celiac Disease

British & Irish 27.7%

23andMe Users 21.4%

Celiac Disease

HLA-DQ8 variant

Celiac disease is an autoimmune condition in which the consumption of gluten (found in wheat, barley, and rye) can result in damage to the small intestine. Celiac disease can lead to both digestive and non-digestive problems. The 23andMe Health + Ancestry DNA test includes two common variants associated with an increased risk of developing this condition. Learn more about Celiac Disease

British & Irish 18.9%

23andMe Users 20.0%

Hereditary Hemochromatosis (HFE-Related)

C282Y variant

Hereditary hemochromatosis is a genetic condition characterized by absorption of too much dietary iron. This may lead to iron overload, which can cause damage to the joints and certain organs, such as the liver, skin, heart, and pancreas. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this condition. Learn more about Hereditary Hemochromatosis (HFE-Related)

British & Irish 17.6%

23andMe Users 9.8%

Alpha-1 Antitrypsin Deficiency

PI*S variant

AAT deficiency is a genetic condition that can lead to lung and liver disease. It is caused by decreased levels of the alpha-1 antitrypsin (AAT) protein. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this deficiency: the PI*S and PI*Z variants in the SERPINA1 gene. Learn more about Alpha-1 Antitrypsin Deficiency

British & Irish 9.5%

23andMe Users 7.3%

Hereditary Thrombophilia

Factor V Leiden variant

Hereditary thrombophilia is a predisposition to developing harmful blood clots. These harmful blood clots most commonly form in the legs and can travel to the lungs. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to hereditary thrombophilia. Learn more about Hereditary Thrombophilia

British & Irish 4.2%

23andMe Users 4.5%

Alpha-1 Antitrypsin Deficiency

PI*Z variant

AAT deficiency is a genetic condition that can lead to lung and liver disease. It is caused by decreased levels of the alpha-1 antitrypsin (AAT) protein. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this deficiency: the PI*S and PI*Z variants in the SERPINA1 gene. Learn more about Alpha-1 Antitrypsin Deficiency

British & Irish 4.0%

23andMe Users 2.9%

Cystic Fibrosis

DeltaF508 variant

Cystic fibrosis is a rare genetic disorder characterized by impaired lung and digestive function. A person must have two variants in the CFTR gene in order to have this condition. Learn more about Cystic Fibrosis

British & Irish 3.5%

23andMe Users 2.3%

Age-Related Macular Degeneration

Y402H variant

Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss among older adults. The disease results in damage to the central part of the retina (the macula), impairing vision needed for reading, driving, or even recognizing faces. The 23andMe Health + Ancestry DNA test includes the two most common variants associated with an increased risk of developing the condition: the Y402H variant in the CFH gene and the A69S variant in the ARMS2 gene. Learn more about Age-Related Macular Degeneration

British & Irish 62.1%

23andMe Users 57.2%

Hereditary Hemochromatosis (HFE-Related)

H63D variant

Hereditary hemochromatosis is a genetic condition characterized by absorption of too much dietary iron. This may lead to iron overload, which can cause damage to the joints and certain organs, such as the liver, skin, heart, and pancreas. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this condition. Learn more about Hereditary Hemochromatosis (HFE-Related)

British & Irish 28.3%

23andMe Users 25.0%

Late-Onset Alzheimer's Disease

ε4 variant

Alzheimer's disease is characterized by memory loss, cognitive decline, and personality changes. Late-onset Alzheimer's disease is the most common form of Alzheimer's disease, developing after age 65. Many factors, including genetics, can influence a person's chances of developing the condition. The 23andMe Health + Ancestry DNA test includes the most common genetic variant associated with late-onset Alzheimer's disease: the ε4 variant in the APOE gene. Learn more about Late-Onset Alzheimer's Disease

British & Irish 28.2%

23andMe Users 25.5%

Celiac Disease

HLA-DQ2.5 variant

Celiac disease is an autoimmune condition in which the consumption of gluten (found in wheat, barley, and rye) can result in damage to the small intestine. Celiac disease can lead to both digestive and non-digestive problems. The 23andMe Health + Ancestry DNA test includes two common variants associated with an increased risk of developing this condition. Learn more about Celiac Disease

British & Irish 27.7%

23andMe Users 21.4%

Celiac Disease

HLA-DQ8 variant

Celiac disease is an autoimmune condition in which the consumption of gluten (found in wheat, barley, and rye) can result in damage to the small intestine. Celiac disease can lead to both digestive and non-digestive problems. The 23andMe Health + Ancestry DNA test includes two common variants associated with an increased risk of developing this condition. Learn more about Celiac Disease

British & Irish 18.9%

23andMe Users 20.0%

Hereditary Hemochromatosis (HFE-Related)

C282Y variant

Hereditary hemochromatosis is a genetic condition characterized by absorption of too much dietary iron. This may lead to iron overload, which can cause damage to the joints and certain organs, such as the liver, skin, heart, and pancreas. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this condition. Learn more about Hereditary Hemochromatosis (HFE-Related)

British & Irish 17.6%

23andMe Users 9.8%

Alpha-1 Antitrypsin Deficiency

PI*S variant

AAT deficiency is a genetic condition that can lead to lung and liver disease. It is caused by decreased levels of the alpha-1 antitrypsin (AAT) protein. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this deficiency: the PI*S and PI*Z variants in the SERPINA1 gene. Learn more about Alpha-1 Antitrypsin Deficiency

British & Irish 9.5%

23andMe Users 7.3%

Hereditary Thrombophilia

Factor V Leiden variant

Hereditary thrombophilia is a predisposition to developing harmful blood clots. These harmful blood clots most commonly form in the legs and can travel to the lungs. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to hereditary thrombophilia. Learn more about Hereditary Thrombophilia

British & Irish 4.2%

23andMe Users 4.5%

Alpha-1 Antitrypsin Deficiency

PI*Z variant

AAT deficiency is a genetic condition that can lead to lung and liver disease. It is caused by decreased levels of the alpha-1 antitrypsin (AAT) protein. The 23andMe Health + Ancestry DNA test includes the two most common variants linked to this deficiency: the PI*S and PI*Z variants in the SERPINA1 gene. Learn more about Alpha-1 Antitrypsin Deficiency

British & Irish 4.0%

23andMe Users 2.9%

Cystic Fibrosis

DeltaF508 variant

Cystic fibrosis is a rare genetic disorder characterized by impaired lung and digestive function. A person must have two variants in the CFTR gene in order to have this condition. Learn more about Cystic Fibrosis

British & Irish 3.5%

23andMe Users 2.3%

Meaning, Origin & Family History (2024)
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